| Game Date |
| Opponent | Conference Game | Result | Commentary |
| 2/19/2010 |
| West Virginia |
| W 4-2 | Caravelle Resort Tournament, Conway, SC |
| 2/20/2010 |
| Virginia Tech |
| W 13-5 | Caravelle Resort Tournament, Conway, SC |
| 2/21/2010 |
| Kentucky |
| L 3-2 | Caravelle Resort Tournament, Conway, SC |
| 2/23/2010 | at | Wake Forest |
| W 2-0 |
|
| 2/25/2010 |
| UC Irvine |
|
| PPD to 2/27, cold (Baseball at the Beach, Myrtle Beach, SC) |
| 2/26/2010 |
| James Madison |
| W 11-7 | Baseball at the Beach, Myrtle Beach, SC |
| 2/27/2010 |
| UC Irvine |
| W 7-3 | Baseball at the Beach, Myrtle Beach, SC |
| 2/27/2010 |
| UC Irvine |
| W 13-6 | makeup of 2/25 game (Baseball at the Beach, Myrtle Beach, SC) |
| 2/28/2010 |
| NC State |
| W 6-3 | Baseball at the Beach, Myrtle Beach, SC |
| 3/5/2010 |
| Toledo |
| W 14-4 | Caravelle Resort Invitational, Conway, SC |
| 3/6/2010 |
| Pittsburgh |
| W 9-6 | Caravelle Resort Invitational, Conway, SC |
| 3/7/2010 |
| Ball State |
| W 3-2 | Caravelle Resort Invitational, Conway, SC |
| 3/8/2010 |
| Ball State |
| W 3-2 |
|
| 3/9/2010 |
| Wake Forest |
| W 9-4 |
|
| 3/12/2010 |
| Illinois |
| L 11-10 | Caravelle Resort Classic, Conway, SC |
| 3/13/2010 |
| Michigan |
| W 13-4 | Caravelle Resort Classic, Conway, SC |
| 3/13/2010 |
| Illinois |
| W 9-4 | Caravelle Resort Classic, Conway, SC |
| 3/14/2010 |
| Michigan |
| W 3-0 | Caravelle Resort Classic, Conway, SC |
| 3/16/2010 | at | College of Charleston |
| L 5-4 |
|
| 3/19/2010 | at | Charleston Southern | * | W 7-5 |
|
| 3/20/2010 | at | Charleston Southern | * | W 29-13 |
|
| 3/21/2010 | at | Charleston Southern | * |
| CCD, rain |
| 3/23/2010 | at | The Citadel |
| W 7-1 |
|
| 3/26/2010 |
| San Diego |
| W 10-2 |
|
| 3/27/2010 |
| San Diego |
| L 5-3 |
|
| 3/28/2010 |
| San Diego |
| L 2-1 |
|
| 3/31/2010 | at | Clemson |
| W 4-3 | 11 innings |
| 4/2/2010 |
| Presbyterian | * | W 14-1 |
|
| 4/3/2010 |
| Presbyterian | * | W 25-2 |
|
| 4/3/2010 |
| Presbyterian | * | W 5-2 |
|
| 4/6/2010 |
| UNC Wilmington |
| W 20-1 |
|
| 4/9/2010 |
| High Point | * | W 10-9 |
|
| 4/10/2010 |
| High Point | * | W 14-4 |
|
| 4/11/2010 |
| High Point | * | W 7-2 |
|
| 4/13/2010 |
| The Citadel |
| W 7-3 |
|
| 4/14/2010 | at | North Carolina |
| W 12-4 |
|
| 4/16/2010 | at | Gardner-Webb | * | W 8-2 |
|
| 4/17/2010 | at | Gardner-Webb | * | W 24-10 |
|
| 4/18/2010 | at | Gardner-Webb | * | W 13-0 |
|
| 4/21/2010 | at | UNC Wilmington |
| W 8-4 |
|
| 4/23/2010 | at | VMI | * | W 7-0 |
|
| 4/24/2010 | at | VMI | * | W 3-2 |
|
| 4/25/2010 | at | VMI | * | W 6-2 |
|
| 4/27/2010 | at | Virginia |
| L 6-3 |
|
| 4/30/2010 |
| UNC Asheville | * | W 18-2 |
|
| 5/1/2010 |
| UNC Asheville | * | W 6-4 |
|
| 5/2/2010 |
| UNC Asheville | * | W 7-1 |
|
| 5/8/2010 |
| Winthrop | * | W 20-3 |
|
| 5/9/2010 |
| Winthrop | * | W 11-7 |
|
| 5/10/2010 |
| Winthrop | * | W 10-4 |
|
| 5/14/2010 | at | Liberty | * | W 5-2 |
|
| 5/15/2010 | at | Liberty | * | W 7-1 |
|
| 5/16/2010 | at | Liberty | * | W 5-0 |
|
| 5/18/2010 |
| College of Charleston |
| L 10-4 | Myrtle Beach, SC |
| 5/20/2010 | at | Radford | * | W 7-2 |
|
| 5/21/2010 | at | Radford | * | W 8-6 |
|
| 5/22/2010 | at | Radford | * |
| CCD, rain |
| 5/26/2010 | vs | VMI | BIGSOUTH-03 | W 11-2 | Big South Tournament, Game 3 (Rock Hill, SC) |
| 5/27/2010 | vs | Radford | BIGSOUTH-07 | W 11-9 | Big South Tournament, Game 7 (Rock Hill, SC) |
| 5/28/2010 | vs | High Point | BIGSOUTH-09 | W 15-9 | Big South Tournament, Game 9 (Rock Hill, SC) |
| 5/29/2010 | vs | Liberty | BIGSOUTH-12 | W 8-2 | Big South Tournament, Game 12 (Rock Hill, SC) |
| 6/4/2010 | vs | Stony Brook |
| W 6-0 | Myrtle Beach Regional, Game 1 |
| 6/5/2010 | vs | College of Charleston |
| L 16-6 | Myrtle Beach Regional, Game 4 |
| 6/6/2010 | vs | Stony Brook |
| W 25-7 | Myrtle Beach Regional, Game 5 |
| 6/6/2010 | vs | College of Charleston |
| W 8-7 | Myrtle Beach Regional, Game 6 |
| 6/7/2010 | vs | College of Charleston |
| W 11-10 | Myrtle Beach Regional, Game 7 (10 innings) |
| 6/12/2010 | vs | South Carolina |
| L 4-3 | Myrtle Beach Super Regional, Game 1 |
| 6/13/2010 | vs | South Carolina |
| L 10-9 | Myrtle Beach Super Regional, Game 2 |
| Game Date |
| Opponent | Conference Game | Result | Commentary |
| 2/19/2010 | at | Kennesaw State |
| W 10-4 |
|
| 2/20/2010 | at | Kennesaw State |
| W 11-2 |
|
| 2/21/2010 | at | Kennesaw State |
| W 10-4 |
|
| 2/23/2010 | at | VCU |
|
| CCD, field conditions |
| 2/26/2010 | vs | Morehead State |
| W 5-2 | Hughes Brothers Challenge, Wilmington, NC |
| 2/27/2010 | vs | Lehigh |
| W 6-3 | Hughes Brothers Challenge, Wilmington, NC |
| 2/28/2010 | at | UNC Wilmington |
| W 12-2 | Hughes Brothers Challenge, Wilmington, NC |
| 3/2/2010 |
| VCU |
|
| PPD to 3/31, inclement weather |
| 3/5/2010 |
| Delaware State |
| W 8-1 |
|
| 3/6/2010 |
| Delaware State |
| W 16-0 | 7 innings |
| 3/7/2010 |
| Delaware State |
| W 10-1 |
|
| 3/9/2010 |
| Old Dominion |
| L 5-3 |
|
| 3/12/2010 |
| St. John's |
| W 9-1 |
|
| 3/13/2010 |
| St. John's |
| W 14-9 |
|
| 3/14/2010 |
| St. John's |
| L 7-6 | 11 innings |
| 3/16/2010 | at | James Madison |
| L 13-2 |
|
| 3/17/2010 | at | Duke |
| L 3-2 | 11 innings (Cary, NC) |
| 3/19/2010 |
| Manhattan |
| W 8-4 |
|
| 3/20/2010 |
| Manhattan |
| L 14-13 | 10 innings |
| 3/21/2010 |
| Manhattan |
| W 8-6 |
|
| 3/24/2010 | at | Virginia Tech |
| L 10-0 | moved from 3/23, impending weather |
| 3/26/2010 | at | UNC Asheville | * | L 5-4 |
|
| 3/27/2010 | at | UNC Asheville | * | L 2-1 |
|
| 3/27/2010 | at | UNC Asheville | * | W 7-3 | moved from 3/28, impending weather |
| 3/30/2010 |
| George Mason |
| W 9-7 |
|
| 3/31/2010 | at | VCU |
| W 7-4 | makeup of 3/2 game |
| 4/2/2010 |
| High Point | * | W 6-4 |
|
| 4/3/2010 |
| High Point | * | W 14-8 |
|
| 4/3/2010 |
| High Point | * | L 5-4 |
|
| 4/6/2010 | at | Old Dominion |
| W 12-9 |
|
| 4/9/2010 | at | Radford | * | W 10-3 |
|
| 4/10/2010 | at | Radford | * | W 3-1 |
|
| 4/11/2010 | at | Radford | * | W 7-6 |
|
| 4/13/2010 |
| Elon |
| L 5-3 |
|
| 4/16/2010 |
| VMI | * | W 12-9 |
|
| 4/17/2010 |
| VMI | * | W 9-6 |
|
| 4/18/2010 |
| VMI | * | W 13-8 |
|
| 4/20/2010 |
| Duke |
| L 4-1 |
|
| 4/21/2010 |
| James Madison |
| W 12-7 |
|
| 4/23/2010 | at | Presbyterian | * | W 8-7 |
|
| 4/24/2010 | at | Presbyterian | * | W 13-0 |
|
| 4/24/2010 | at | Presbyterian | * |
| PPD to 4/25, rain (moved from 4/25, impending weather) |
| 4/25/2010 | at | Presbyterian | * | W 16-9 | 10 innings (makeup of 4/24 game) |
| 4/27/2010 | at | Elon |
| L 3-1 |
|
| 4/30/2010 |
| Gardner-Webb | * | W 11-2 |
|
| 5/1/2010 |
| Gardner-Webb | * | W 9-4 |
|
| 5/2/2010 |
| Gardner-Webb | * | W 10-7 |
|
| 5/4/2010 | at | George Mason |
| W 16-7 |
|
| 5/5/2010 |
| Maryland |
| W 11-1 |
|
| 5/7/2010 | at | Charleston Southern | * | W 7-5 |
|
| 5/8/2010 | at | Charleston Southern | * | W 4-1 |
|
| 5/9/2010 | at | Charleston Southern | * | W 13-4 |
|
| 5/14/2010 |
| Coastal Carolina | * | L 5-2 |
|
| 5/15/2010 |
| Coastal Carolina | * | L 7-1 |
|
| 5/16/2010 |
| Coastal Carolina | * | L 5-0 |
|
| 5/18/2010 |
| VCU |
| W 7-6 |
|
| 5/20/2010 | at | Winthrop | * | W 8-2 |
|
| 5/21/2010 | at | Winthrop | * | L 11-2 |
|
| 5/22/2010 | at | Winthrop | * | L 8-5 |
|
| 5/26/2010 | vs | Winthrop | BIGSOUTH-04 | W 7-2 | Big South Tournament, Game 4 (Rock Hill, SC) |
| 5/27/2010 | vs | High Point | BIGSOUTH-08 | L 2-1 | Big South Tournament, Game 8 (Rock Hill, SC) |
| 5/28/2010 | vs | Winthrop | BIGSOUTH-10 | W 9-7 | Big South Tournament, Game 10 (Rock Hill, SC) |
| 5/28/2010 | vs | High Point | BIGSOUTH-11 |
| Big South Tournament, Game 11 (Rock Hill, SC) (PPD, rain) |
| 5/29/2010 | vs | High Point | BIGSOUTH-11 | W 9-5 | Big South Tournament, Game 11 (Rock Hill, SC) (makeup of 5/28 game) |
| 5/29/2010 | vs | Coastal Carolina | BIGSOUTH-12 | L 8-2 | Big South Tournament, Game 12 (Rock Hill, SC) |
| Game Date |
| Opponent | Conference Game | Result | Commentary |
| 2/19/2010 | at | College of Charleston |
| L 8-4 |
|
| 2/20/2010 | at | College of Charleston |
| L 9-1 |
|
| 2/21/2010 | at | College of Charleston |
| L 11-3 |
|
| 2/26/2010 | vs | Marshall |
| L 3-2 | Charleston Crab House Shootout, Charleston, SC |
| 2/27/2010 | vs | St. Joseph's |
| W 11-2 | Charleston Crab House Shootout, Charleston, SC |
| 2/28/2010 | at | The Citadel |
| L 15-4 | Charleston Crab House Shootout, Charleston, SC |
| 3/2/2010 | at | Virginia Tech |
|
| PPD to 3/3, impending weather |
| 3/3/2010 | at | Virginia Tech |
|
| PPD, field conditions (makeup of 3/2 game) |
| 3/5/2010 | vs | Princeton |
| W 9-8 | 11 innings (Elon Invitational, Elon, NC) |
| 3/6/2010 | vs | Bucknell |
| W 4-2 | Elon Invitational, Elon, NC |
| 3/7/2010 | at | Elon |
| L 7-6 | Elon Invitational, Elon, NC |
| 3/9/2010 |
| George Mason |
| L 9-5 |
|
| 3/13/2010 |
| Rider |
| W 7-2 |
|
| 3/14/2010 |
| Rider |
| W 4-3 |
|
| 3/14/2010 |
| Rider |
| W 1-0 | 8 innings |
| 3/17/2010 | at | North Carolina A&T |
| W 9-2 |
|
| 3/19/2010 |
| UNC Asheville | * | W 6-5 | 12 innings |
| 3/20/2010 |
| UNC Asheville | * | W 10-2 |
|
| 3/21/2010 |
| UNC Asheville | * | W 5-4 |
|
| 3/24/2010 | at | Virginia Tech |
|
| CCD, impending weather (makeup of 3/3 game) |
| 3/24/2010 | at | East Tennessee State |
| L 22-10 | moved from 3/23, impending weather |
| 3/27/2010 |
| Siena |
| W 14-5 |
|
| 3/27/2010 |
| Siena |
| W 4-3 | 7 innings |
| 3/28/2010 |
| Siena |
| L 9-6 | 12 innings |
| 3/30/2010 | at | James Madison |
| L 9-2 |
|
| 4/2/2010 |
| Charleston Southern | * | L 7-5 |
|
| 4/3/2010 |
| Charleston Southern | * | L 9-6 |
|
| 4/3/2010 |
| Charleston Southern | * | W 9-3 |
|
| 4/7/2010 | at | Virginia |
| L 12-2 |
|
| 4/9/2010 |
| Liberty | * | L 10-3 |
|
| 4/10/2010 |
| Liberty | * | L 3-1 |
|
| 4/11/2010 |
| Liberty | * | L 7-6 |
|
| 4/13/2010 |
| James Madison |
| W 15-12 |
|
| 4/14/2010 |
| Longwood |
| W 8-2 |
|
| 4/16/2010 | at | High Point | * | W 9-4 |
|
| 4/17/2010 | at | High Point | * | L 13-12 |
|
| 4/18/2010 | at | High Point | * | W 18-17 |
|
| 4/20/2010 |
| Virginia Tech |
| L 16-6 |
|
| 4/21/2010 |
| North Carolina A&T |
| W 9-5 |
|
| 4/23/2010 | at | Winthrop | * | W 15-9 |
|
| 4/24/2010 | at | Winthrop | * |
| PPD to 4/25, rain |
| 4/25/2010 | at | Winthrop | * | L 8-5 |
|
| 4/25/2010 | at | Winthrop | * | W 9-4 | makeup of 4/24 game |
| 4/27/2010 |
| East Tennessee State |
| W 9-8 | 10 innings |
| 4/30/2010 | at | VMI | * | W 9-2 |
|
| 5/1/2010 | at | VMI | * | W 15-6 |
|
| 5/2/2010 | at | VMI | * | L 7-5 |
|
| 5/7/2010 |
| Presbyterian | * | W 7-6 | 12 innings |
| 5/8/2010 |
| Presbyterian | * | W 12-1 |
|
| 5/9/2010 |
| Presbyterian | * | W 7-3 |
|
| 5/11/2010 | at | Longwood |
| L 9-6 |
|
| 5/14/2010 | at | Gardner-Webb | * | W 11-10 |
|
| 5/15/2010 | at | Gardner-Webb | * | W 6-5 |
|
| 5/15/2010 | at | Gardner-Webb | * | L 5-4 | 10 innings (moved from 5/16, impending weather) |
| 5/18/2010 | vs | Marshall |
| W 15-5 | Beckley, WV |
| 5/20/2010 |
| Coastal Carolina | * | L 7-2 |
|
| 5/21/2010 |
| Coastal Carolina | * | L 8-6 |
|
| 5/22/2010 |
| Coastal Carolina | * |
| CCD, rain |
| 5/26/2010 | vs | High Point | BIGSOUTH-05 | L 10-8 | Big South Tournament, Game 5 (Rock Hill, SC) |
| 5/27/2010 | vs | Coastal Carolina | BIGSOUTH-07 | L 11-9 | Big South Tournament, Game 7 (Rock Hill, SC) |
| Game Date |
| Opponent | Conference Game | Result | Commentary |
| 2/19/2010 |
| Northwestern |
| W 8-4 | Bojangles Baseball Classic, Rock Hill, SC |
| 2/20/2010 |
| George Mason |
| W 11-4 | Bojangles Baseball Classic, Rock Hill, SC |
| 2/21/2010 |
| Marist |
| W 19-4 | Bojangles Baseball Classic, Rock Hill, SC |
| 2/22/2010 |
| Marist |
| W 10-9 | Bojangles Baseball Classic, Rock Hill, SC |
| 2/26/2010 |
| Wagner |
| W 3-2 |
|
| 2/27/2010 |
| Wagner |
| W 4-3 |
|
| 2/28/2010 |
| Wagner |
| W 16-4 |
|
| 3/2/2010 | at | Wake Forest |
|
| PPD to 3/3, inclement weather |
| 3/3/2010 | at | Wake Forest |
|
| PPD, field conditions (makeup of 3/2 game) |
| 3/5/2010 | at | Texas A&M |
| L 7-0 |
|
| 3/6/2010 | at | Texas A&M |
| L 12-4 |
|
| 3/7/2010 | at | Texas A&M |
| L 2-1 |
|
| 3/11/2010 |
| Toledo |
| L 5-4 | Johnny Gill Memorial Tournament, Rock Hill, SC |
| 3/12/2010 |
| Toledo |
| W 5-4 | Johnny Gill Memorial Tournament, Rock Hill, SC |
| 3/13/2010 |
| Canisius |
| W 3-2 | Johnny Gill Memorial Tournament, Rock Hill, SC |
| 3/14/2010 |
| Canisius |
| L 3-1 | Johnny Gill Memorial Tournament, Rock Hill, SC |
| 3/16/2010 |
| Harvard |
| W 12-5 |
|
| 3/18/2010 |
| Columbia |
| L 4-2 |
|
| 3/19/2010 |
| Columbia |
| W 11-5 | Coca-Cola Classic, Rock Hill, SC |
| 3/20/2010 |
| Kent State |
| L 16-10 | Coca-Cola Classic, Rock Hill, SC |
| 3/20/2010 |
| Penn State |
| W 14-13 | 10 innings (Coca-Cola Classic, Rock Hill, SC) |
| 3/21/2010 |
| Columbia |
|
| CCD, rain (Coca-Cola Classic, Rock Hill, SC) |
| 3/24/2010 | at | The Citadel |
| L 7-3 |
|
| 3/26/2010 |
| High Point | * | L 15-4 |
|
| 3/27/2010 |
| High Point | * | L 15-9 |
|
| 3/27/2010 |
| High Point | * | W 8-4 | moved from 3/28, impending weather |
| 3/30/2010 | at | North Carolina |
| L 14-5 |
|
| 4/2/2010 | at | Gardner-Webb | * | L 5-4 |
|
| 4/3/2010 | at | Gardner-Webb | * | L 3-1 |
|
| 4/3/2010 | at | Gardner-Webb | * | L 4-3 |
|
| 4/7/2010 |
| The Citadel |
| L 10-8 | 11 innings |
| 4/9/2010 | at | Charleston Southern | * | L 7-5 |
|
| 4/10/2010 | at | Charleston Southern | * | W 2-1 |
|
| 4/11/2010 | at | Charleston Southern | * | W 7-3 |
|
| 4/14/2010 | at | Charlotte |
| L 16-5 |
|
| 4/16/2010 | at | UNC Asheville | * | W 12-11 | 13 innings |
| 4/17/2010 | at | UNC Asheville | * | W 15-3 |
|
| 4/18/2010 | at | UNC Asheville | * | W 10-8 |
|
| 4/21/2010 | at | Georgia |
| L 4-2 |
|
| 4/23/2010 |
| Radford | * | L 15-9 |
|
| 4/24/2010 |
| Radford | * |
| PPD to 4/25, rain |
| 4/25/2010 |
| Radford | * | W 8-5 |
|
| 4/25/2010 |
| Radford | * | L 9-4 | makeup of 4/24 game |
| 4/27/2010 |
| Charlotte |
|
| PPD, inclement weather |
| 5/1/2010 |
| Presbyterian | * | W 15-12 |
|
| 5/1/2010 |
| Presbyterian | * | W 4-0 |
|
| 5/2/2010 |
| Presbyterian | * | L 8-7 | 13 innings |
| 5/5/2010 | at | South Carolina |
| L 14-6 |
|
| 5/8/2010 | at | Coastal Carolina | * | L 20-3 |
|
| 5/9/2010 | at | Coastal Carolina | * | L 11-7 |
|
| 5/10/2010 | at | Coastal Carolina | * | L 10-4 |
|
| 5/11/2010 |
| Wake Forest |
|
| CCD, scheduling conflict |
| 5/14/2010 | at | VMI | * | W 6-5 |
|
| 5/15/2010 | at | VMI | * | W 8-2 |
|
| 5/16/2010 | at | VMI | * | L 7-5 |
|
| 5/18/2010 |
| The Citadel |
| L 10-4 |
|
| 5/20/2010 |
| Liberty | * | L 8-2 |
|
| 5/21/2010 |
| Liberty | * | W 11-2 |
|
| 5/22/2010 |
| Liberty | * | W 8-5 |
|
| 5/25/2010 | vs | Gardner-Webb | BIGSOUTH-02 | W 4-3 | Big South Tournament, Game 2 (Rock Hill, SC) |
| 5/26/2010 | vs | Liberty | BIGSOUTH-04 | L 7-2 | Big South Tournament, Game 4 (Rock Hill, SC) |
| 5/27/2010 | vs | VMI | BIGSOUTH-06 | W 11-6 | Big South Tournament, Game 6 (Rock Hill, SC) |
| 5/28/2010 | vs | Liberty | BIGSOUTH-10 | L 9-7 | Big South Tournament, Game 10 (Rock Hill, SC) |