| Game Date | Conference | Road Team | Score |
| Home Team | Score | Box Score | Recap | Commentary |
| 2/19/2010 |
| Bethune-Cookman | 4 | vs | Cal State Northridge | 18 | Box Score | Recap | MLB Urban Invitational, Compton, CA |
| 2/19/2010 |
| Coppin State |
| at | Longwood |
| | Recap | CCD, snow (Longwood Tournament, Farmville, VA) |
| 2/19/2010 |
| Florida A&M | 1 | vs | Richmond | 23 | Box Score | Recap | North Florida Tournament, Jacksonville, FL |
| 2/19/2010 |
| Navy | 13 | vs | Delaware State | 3 | Box Score | Recap | Eagle Baseball Classic, Durham, NC |
| 2/19/2010 |
| North Carolina A&T | 6 | vs | Ohio | 2 | Box Score | Recap | Elon Tournament, Elon, NC |
| 2/19/2010 |
| UMES | 0 | at | William and Mary | 24 | Box Score | Recap |
|
| 2/19/2010 |
| Villanova | 13 | at | Norfolk State | 2 | Box Score | Recap |
|
| 2/20/2010 |
| Coppin State |
| at | Longwood |
| | Recap | CCD, snow (Longwood Tournament, Farmville, VA) |
| 2/20/2010 |
| Coppin State |
| vs | Penn State |
| | Recap | CCD, snow (Longwood Tournament, Farmville, VA) |
| 2/20/2010 |
| Delaware State | 26 | at | North Carolina Central | 2 | Box Score | Recap | Eagle Baseball Classic, Durham, NC |
| 2/20/2010 |
| Florida A&M | 1 | vs | Ohio State | 16 | Box Score | Recap | North Florida Tournament, Jacksonville, FL |
| 2/20/2010 |
| Towson | 8 | vs | North Carolina A&T | 1 | Box Score | Recap | Elon Tournament, Elon, NC |
| 2/20/2010 |
| UCLA | 10 | vs | Bethune-Cookman | 3 | Box Score | Recap | MLB Urban Invitational, Compton, CA |
| 2/20/2010 |
| UMES | 7 | at | William and Mary | 11 | Box Score | Recap |
|
| 2/20/2010 |
| Villanova | 7 | at | Norfolk State | 3 | Box Score | Recap |
|
| 2/21/2010 |
| Delaware State | 12 | vs | Iona | 3 | Box Score | Recap | Eagle Baseball Classic, Durham, NC |
| 2/21/2010 |
| Florida A&M | 5 | at | North Florida | 6 | Box Score | Recap | North Florida Tournament, Jacksonville, FL |
| 2/21/2010 |
| North Carolina A&T | 0 | at | Elon | 14 | Box Score | Recap | Elon Tournament, Elon, NC |
| 2/21/2010 |
| Southern | 8 | vs | Bethune-Cookman | 13 | Box Score | Recap | MLB Urban Invitational, Compton, CA |
| 2/21/2010 |
| UMES | 0 | at | William and Mary | 5 | Box Score | Recap |
|
| 2/21/2010 |
| Villanova | 10 | at | Norfolk State | 1 | Box Score | Recap |
|
| 2/22/2010 |
| Bethune-Cookman | 1 | at | UC Riverside | 6 | Box Score | Recap |
|
| 2/23/2010 |
| Mercer |
| at | Florida A&M |
| | Recap | PPD to 3/9, field conditions |
| 2/24/2010 |
| UMES | 10 | at | Navy | 12 | Box Score | Recap |
|
| 2/25/2010 |
| Bethune-Cookman | 8 | at | Texas Tech | 12 | Box Score | Recap | Brooks Wallace Memorial Classic, Lubbock, TX |
| 2/26/2010 |
| Campbell | 15 | at | North Carolina A&T | 5 | Box Score | Recap |
|
| 2/26/2010 |
| Coppin State | 1 | at | George Washington | 11 | Box Score | Recap |
|
| 2/26/2010 |
| Delaware State | 6 | vs | Florida A&M | 8 | Box Score | Recap | Savannah State Classic, Savannah, GA |
| 2/26/2010 |
| Delaware State | 12 | at | Savannah State | 10 | Box Score | Recap | 8 innings (Savannah State Classic, Savannah, GA) |
| 2/26/2010 |
| Rider |
| at | UMES |
| | Recap | PPD to 2/27, field conditions |
| 2/26/2010 |
| Washington State | 10 | vs | Bethune-Cookman | 4 | Box Score | Recap | Brooks Wallace Memorial Classic, Lubbock, TX |
| 2/27/2010 |
| Bethune-Cookman | 12 | at | Texas Tech | 14 | Box Score | Recap | Brooks Wallace Memorial Classic, Lubbock, TX |
| 2/27/2010 |
| Bethune-Cookman | 3 | vs | Washington State | 6 | Box Score | Recap | Brooks Wallace Memorial Classic, Lubbock, TX |
| 2/27/2010 |
| Coppin State | 4 | at | George Washington | 11 | Box Score | Recap |
|
| 2/27/2010 |
| Coppin State | 3 | at | George Washington | 16 | Box Score | Recap | 7 innings |
| 2/27/2010 |
| Delaware State | 2 | vs | Norfolk State | 5 | Box Score | Recap | Savannah State Classic, Savannah, GA |
| 2/27/2010 |
| Florida A&M | 12 | vs | Norfolk State | 12 | Box Score | Recap | 8 innings, darkness (Savannah State Classic, Savannah, GA) |
| 2/27/2010 |
| Florida A&M | 16 | at | Savannah State | 14 | Box Score | | Savannah State Classic, Savannah, GA |
| 2/27/2010 |
| North Carolina A&T | 5 | at | Campbell | 14 | Box Score | Recap |
|
| 2/27/2010 |
| North Carolina A&T | 5 | at | Campbell | 3 | Box Score | Recap |
|
| 2/27/2010 |
| Rider |
| at | UMES |
| | Recap | PPD to 3/1, field conditions |
| 2/27/2010 |
| Rider |
| at | UMES |
| | Recap | PPD to 3/1, field conditions (makeup of 2/26 game) |
| 2/28/2010 |
| Norfolk State | 13 | at | Savannah State | 5 | Box Score | Recap | Savannah State Classic, Savannah, GA |
| 2/28/2010 |
| Rider | 8 | at | UMES | 0 | Box Score | Recap |
|
| 2/28/2010 |
| Rider | 2 | at | UMES | 0 | Box Score | Recap | 7 innings |
| 3/1/2010 |
| Coppin State | 10 | at | Longwood | 11 | Box Score | Recap | 7 innings |
| 3/1/2010 |
| Coppin State | 5 | at | Longwood | 14 | Box Score | Recap | 7 innings |
| 3/1/2010 |
| Rider | 4 | at | UMES | 1 | Box Score | Recap | makeup of 2/27 game |
| 3/1/2010 |
| Rider | 7 | at | UMES | 0 | Box Score | Recap | 7 innings (makeup of 2/27 game) |
| 3/2/2010 |
| Charlotte |
| at | North Carolina A&T |
| | Recap | PPD to 3/23, impending weather |
| 3/2/2010 |
| Georgetown | 4 | at | Norfolk State | 7 | Box Score | Recap |
|
| 3/2/2010 |
| Mercer |
| at | Florida A&M |
| | Recap | CCD, inclement weather |
| 3/2/2010 |
| Stetson | 10 | at | Bethune-Cookman | 11 | Box Score | Recap |
|
| 3/3/2010 |
| Appalachian State |
| at | North Carolina A&T |
| | Recap | PPD to 4/6, field conditions |
| 3/3/2010 |
| Jacksonville | 3 | at | Bethune-Cookman | 4 | Box Score | Recap |
|
| 3/3/2010 |
| Lehigh |
| at | UMES |
| | Recap | PPD, impending weather |
| 3/3/2010 |
| Lehigh |
| at | UMES |
| | Recap | PPD, impending weather |
| 3/3/2010 |
| Lincoln (PA) |
| at | Delaware State |
| | Recap | PPD, field conditions |
| 3/3/2010 |
| Lincoln (PA) |
| at | Delaware State |
| | Recap | PPD, field conditions |
| 3/4/2010 |
| Coppin State | 5 | at | Navy | 13 | Box Score | Recap |
|
| 3/5/2010 |
| Bethune-Cookman | 8 | at | Troy | 4 | Box Score | Recap |
|
| 3/5/2010 |
| Delaware State | 1 | at | Liberty | 8 | Box Score | Recap |
|
| 3/5/2010 |
| Jackson State | 6 | at | Florida A&M | 3 | Box Score | Recap |
|
| 3/5/2010 |
| UMES | 4 | at | VMI | 18 | Box Score | Recap |
|
| 3/6/2010 |
| Bethune-Cookman | 2 | at | Troy | 18 | Box Score | Recap |
|
| 3/6/2010 |
| Delaware State | 0 | at | Liberty | 16 | Box Score | Recap | 7 innings |
| 3/6/2010 |
| Iona | 9 | at | Coppin State | 6 | Box Score | Recap |
|
| 3/6/2010 |
| Iona | 13 | at | Coppin State | 2 | Box Score | Recap | 7 innings |
| 3/6/2010 |
| Jackson State | 10 | at | Florida A&M | 11 | Box Score | Recap |
|
| 3/6/2010 |
| Mount St. Mary's | 1 | at | Norfolk State | 2 | Box Score | Recap | 7 innings |
| 3/6/2010 |
| Mount St. Mary's | 5 | at | Norfolk State | 4 | Box Score | Recap | 7 innings |
| 3/6/2010 |
| New Jersey Tech | 13 | at | North Carolina A&T | 12 | Box Score | Recap |
|
| 3/6/2010 |
| New Jersey Tech | 6 | at | North Carolina A&T | 1 | Box Score | Recap | 7 innings |
| 3/6/2010 |
| UMES | 1 | at | VMI | 20 | Box Score | Recap |
|
| 3/7/2010 |
| Bethune-Cookman | 4 | at | Troy | 9 | Box Score | Recap |
|
| 3/7/2010 |
| Delaware State | 1 | at | Liberty | 10 | Box Score | Recap |
|
| 3/7/2010 |
| Iona | 10 | at | Coppin State | 5 | Box Score | Recap |
|
| 3/7/2010 |
| Mount St. Mary's | 7 | at | Norfolk State | 5 | Box Score | Recap |
|
| 3/7/2010 |
| New Jersey Tech | 4 | at | North Carolina A&T | 8 | Box Score | Recap |
|
| 3/7/2010 |
| UMES | 4 | at | VMI | 8 | Box Score | Recap |
|
| 3/9/2010 |
| Mercer | 13 | at | Florida A&M | 3 | Box Score | Recap | makeup of 2/23 game |
| 3/9/2010 |
| North Carolina A&T | 10 | at | NC State | 14 | Box Score | Recap |
|
| 3/9/2010 |
| Virginia State | 3 | at | Coppin State | 10 | Box Score | Recap | 7 innings |
| 3/9/2010 |
| Virginia State | 10 | at | Coppin State | 11 | Box Score | Recap | 7 innings |
| 3/10/2010 |
| Albany State (GA) | 12 | at | Florida A&M | 8 | Box Score | |
|
| 3/10/2010 |
| Delaware State | 6 | at | Temple | 14 | Box Score | Recap |
|
| 3/10/2010 |
| Eastern Kentucky | 4 | at | North Carolina A&T | 1 | Box Score | Recap |
|
| 3/10/2010 |
| Norfolk State | 14 | at | North Carolina Central | 2 | Box Score | Recap | 7 innings |
| 3/10/2010 |
| Norfolk State | 18 | at | North Carolina Central | 6 | Box Score | Recap | 7 innings |
| 3/10/2010 |
| UMES | 2 | at | George Washington | 5 | Box Score | Recap |
|
| 3/10/2010 |
| Wagner | 0 | at | Bethune-Cookman | 10 | Box Score | Recap |
|
| 3/12/2010 |
| Lehigh |
| at | Coppin State |
| | Recap | PPD, inclement weather |
| 3/12/2010 |
| VCU |
| at | Bethune-Cookman |
| | Recap | PPD to 3/13, rain (Bethune-Cookman Invitational, Daytona Beach, FL) |
| 3/12/2010 |
| Wagner |
| at | Bethune-Cookman |
| | Recap | CCD, rain (Bethune-Cookman Invitational, Daytona Beach, FL) |
| 3/13/2010 |
| Binghamton |
| at | UMES |
| | Recap | CCD, inclement weather |
| 3/13/2010 |
| Binghamton |
| at | UMES |
| | Recap | PPD to 3/14, inclement weather |
| 3/13/2010 |
| Fairfield |
| at | Delaware State |
| | Recap | CCD, rain |
| 3/13/2010 |
| Fairfield |
| at | Delaware State |
| | Recap | CCD, rain |
| 3/13/2010 |
| Lehigh |
| at | Coppin State |
| | Recap | PPD, inclement weather |
| 3/13/2010 |
| Lehigh |
| at | Coppin State |
| | Recap | PPD, inclement weather |
| 3/13/2010 |
| North Carolina A&T | 27 | at | North Carolina Central | 6 | Box Score | Recap | 7 innings |
| 3/13/2010 |
| North Carolina A&T |
| at | North Carolina Central |
| | Recap | CCD, rain |
| 3/13/2010 |
| Savannah State | 5 | at | Florida A&M | 10 | Box Score | |
|
| 3/13/2010 |
| VCU | 6 | at | Bethune-Cookman | 10 | Box Score | Recap | makeup of 3/12 game (Bethune-Cookman Invitational, Daytona Beach, FL) |
| 3/13/2010 |
| Wagner | 9 | at | Bethune-Cookman | 14 | Box Score | Recap | Bethune-Cookman Invitational, Daytona Beach, FL |
| 3/14/2010 |
| Binghamton |
| at | UMES |
| | | CCD |
| 3/14/2010 |
| Binghamton |
| at | UMES |
| | | CCD (makeup of 3/12 game) |
| 3/14/2010 |
| Fairfield |
| at | Delaware State |
| | Recap | CCD, rain |
| 3/14/2010 |
| Fairleigh Dickinson |
| at | Norfolk State |
| | Recap | PPD, field conditions |
| 3/14/2010 |
| Fairleigh Dickinson |
| at | Norfolk State |
| | Recap | PPD, field conditions |
| 3/14/2010 |
| North Carolina Central | 2 | at | North Carolina A&T | 28 | Box Score | Recap |
|
| 3/14/2010 |
| Savannah State | 15 | at | Florida A&M | 8 | Box Score | |
|
| 3/14/2010 |
| VCU | 1 | at | Bethune-Cookman | 8 | Box Score | Recap | Bethune-Cookman Invitational, Daytona Beach, FL |
| 3/15/2010 |
| Fairleigh Dickinson |
| at | Norfolk State |
| | Recap | PPD, field conditions (moved from 3/13, impending weather) |
| 3/15/2010 |
| Fairleigh Dickinson |
| at | Norfolk State |
| | Recap | PPD, field conditions (moved from 3/13, impending weather) |
| 3/16/2010 |
| Delaware State | 4 | at | Delaware | 10 | Box Score | Recap | 7 innings |
| 3/16/2010 |
| Delaware State | 0 | at | Delaware | 6 | Box Score | Recap |
|
| 3/16/2010 |
| Florida A&M | 2 | at | Mercer | 17 | Box Score | Recap |
|
| 3/16/2010 |
| High Point | 3 | at | North Carolina A&T | 15 | Box Score | Recap |
|
| 3/16/2010 |
| Norfolk State |
| at | VCU |
| | Recap | CCD, field conditions |
| 3/16/2010 |
| Stetson | 9 | at | Bethune-Cookman | 11 | Box Score | Recap |
|
| 3/16/2010 |
| UMES | 2 | at | Campbell | 14 | Box Score | Recap |
|
| 3/16/2010 |
| UMES | 1 | at | Campbell | 6 | Box Score | Recap | 7 innings |
| 3/17/2010 |
| Florida A&M |
| at | Mercer |
| | Recap | PPD, inclement weather |
| 3/17/2010 |
| Radford | 9 | at | North Carolina A&T | 2 | Box Score | Recap |
|
| 3/17/2010 |
| UMES | 0 | at | Campbell | 13 | Box Score | Recap |
|
| 3/17/2010 |
| Washington (MD) | 3 | at | Coppin State | 2 | Box Score | Recap | 7 innings |
| 3/17/2010 |
| Washington (MD) | 4 | at | Coppin State | 1 | Box Score | Recap | 7 innings |
| 3/18/2010 |
| Princeton | 5 | at | North Carolina A&T | 3 | Box Score | Recap |
|
| 3/19/2010 |
| North Carolina Central | 5 | at | Coppin State | 11 | Box Score | Recap |
|
| 3/20/2010 | * | Bethune-Cookman | 11 | at | Florida A&M | 1 | Box Score | Recap | 7 innings |
| 3/20/2010 | * | Bethune-Cookman | 18 | at | Florida A&M | 0 | Box Score | Recap | 5 innings, run rule |
| 3/20/2010 |
| North Carolina Central | 0 | at | Coppin State | 1 | Box Score | Recap | 7 innings |
| 3/20/2010 |
| North Carolina Central | 5 | at | Coppin State | 6 | Box Score | Recap | 7 innings |
| 3/20/2010 |
| St. Peter's | 3 | at | Delaware State | 2 | Box Score | Recap | 7 innings |
| 3/20/2010 |
| St. Peter's | 14 | at | Delaware State | 6 | Box Score | Recap | 7 innings |
| 3/20/2010 |
| UMES | 3 | at | Savannah State | 13 | Box Score | Recap |
|
| 3/20/2010 |
| UMES | 2 | at | Savannah State | 3 | Box Score | Recap | 7 innings |
| 3/21/2010 | * | Bethune-Cookman | 13 | at | Florida A&M | 0 | Box Score | Recap | 7 innings |
| 3/21/2010 |
| St. Peter's | 8 | at | Delaware State | 3 | Box Score | | 7 innings |
| 3/21/2010 |
| St. Peter's | 5 | at | Delaware State | 3 | Box Score | | 7 innings |
| 3/21/2010 |
| UMES |
| at | Savannah State |
| | Recap | CCD, rain |
| 3/22/2010 |
| Ohio State | 3 | at | Bethune-Cookman | 5 | Box Score | Recap |
|
| 3/23/2010 |
| Charlotte | 15 | at | North Carolina A&T | 4 | Box Score | Recap | makeup of 3/2 game |
| 3/23/2010 |
| Georgetown | 18 | at | Delaware State | 7 | Box Score | Recap |
|
| 3/23/2010 |
| LaSalle |
| at | Coppin State |
| | Recap | PPD to 5/12, rain |
| 3/23/2010 |
| Mount St. Mary's |
| at | UMES |
| | Recap | PPD, impending weather |
| 3/23/2010 |
| Old Dominion | 5 | at | Norfolk State | 12 | Box Score | Recap |
|
| 3/24/2010 |
| North Carolina A&T | 6 | at | East Carolina | 15 | Box Score | Recap |
|
| 3/24/2010 |
| North Florida | 3 | at | Bethune-Cookman | 2 | Box Score | Recap |
|
| 3/24/2010 |
| UMES | 6 | at | LaSalle | 10 | Box Score | Recap | 7 innings |
| 3/24/2010 |
| UMES | 8 | at | LaSalle | 4 | Box Score | Recap | 6 innings |
| 3/25/2010 |
| Dartmouth | 2 | at | Bethune-Cookman | 4 | Box Score | Recap |
|
| 3/25/2010 |
| Selma (AL) | 2 | at | Florida A&M | 9 | Box Score | | 7 innings |
| 3/25/2010 |
| Selma (AL) | 1 | at | Florida A&M | 8 | Box Score | | 7 innings |
| 3/26/2010 |
| Dartmouth | 3 | at | Bethune-Cookman | 4 | Box Score | Recap |
|
| 3/27/2010 |
| Dartmouth | 14 | at | Bethune-Cookman | 12 | Box Score | Recap |
|
| 3/27/2010 | * | Norfolk State | 4 | at | North Carolina A&T | 8 | Box Score | Recap |
|
| 3/27/2010 | * | Norfolk State | 2 | at | North Carolina A&T | 3 | Box Score | Recap |
|
| 3/27/2010 |
| Savannah State | 8 | at | Delaware State | 2 | Box Score | Recap |
|
| 3/27/2010 |
| Savannah State | 11 | at | Delaware State | 5 | Box Score | Recap |
|
| 3/27/2010 | * | UMES |
| at | Coppin State |
| | | PPD to 3/29 |
| 3/27/2010 | * | UMES |
| at | Coppin State |
| | | PPD to 3/28 |
| 3/28/2010 | * | Norfolk State | 4 | at | North Carolina A&T | 8 | Box Score | Recap |
|
| 3/28/2010 |
| Savannah State | 4 | at | Delaware State | 8 | Box Score | Recap |
|
| 3/28/2010 | * | UMES | 0 | at | Coppin State | 11 | Box Score | Recap | 7 innings |
| 3/28/2010 | * | UMES | 0 | at | Coppin State | 5 | Box Score | Recap | 7 innings (makeup of 3/27 game) |
| 3/29/2010 | * | UMES |
| at | Coppin State |
| | Recap | PPD, rain (makeup of 3/27 game) |
| 3/30/2010 |
| Bethune-Cookman | 8 | at | UCF | 11 | Box Score | Recap |
|
| 3/30/2010 |
| Florida A&M | 15 | at | Edward Waters | 16 | Box Score | |
|
| 3/30/2010 |
| Norfolk State | 3 | at | Campbell | 9 | Box Score | Recap |
|
| 3/30/2010 |
| North Carolina A&T | 8 | at | Gardner-Webb | 12 | Box Score | Recap | Cherryville, NC |
| 3/31/2010 |
| Florida A&M | 6 | at | Jacksonville | 12 | Box Score | Recap |
|
| 3/31/2010 |
| George Washington | 6 | at | UMES | 5 | Box Score | Recap |
|
| 3/31/2010 |
| Lehigh | 5 | at | Coppin State | 6 | Box Score | Recap |
|
| 3/31/2010 |
| North Carolina A&T | 5 | at | UNC Greensboro | 12 | Box Score | Recap |
|
| 3/31/2010 |
| UCF | 9 | at | Bethune-Cookman | 7 | Box Score | Recap |
|
| 4/2/2010 | * | Coppin State | 7 | at | Norfolk State | 4 | Box Score | Recap |
|
| 4/2/2010 | * | Coppin State | 2 | at | Norfolk State | 7 | Box Score | Recap | 7 innings |
| 4/2/2010 | * | Delaware State | 9 | at | UMES | 8 | Box Score | Recap |
|
| 4/2/2010 | * | Florida A&M | 4 | at | North Carolina A&T | 13 | Box Score | Recap |
|
| 4/2/2010 | * | Florida A&M | 4 | at | North Carolina A&T | 13 | Box Score | Recap | 7 innings |
| 4/3/2010 | * | Coppin State | 16 | at | Norfolk State | 13 | Box Score | Recap |
|
| 4/3/2010 | * | Delaware State | 18 | at | UMES | 8 | Box Score | Recap | 7 innings |
| 4/3/2010 | * | Delaware State | 3 | at | UMES | 5 | Box Score | Recap |
|
| 4/3/2010 | * | Florida A&M | 7 | at | North Carolina A&T | 25 | Box Score | Recap |
|
| 4/5/2010 |
| Canisius | 18 | at | UMES | 7 | Box Score | Recap |
|
| 4/6/2010 |
| Coppin State | 2 | at | NC State | 11 | Box Score | Recap |
|
| 4/6/2010 |
| North Carolina A&T | 4 | at | Appalachian State | 15 | Box Score | Recap | makeup of 3/3 game |
| 4/6/2010 |
| North Carolina A&T | 2 | at | Appalachian State | 3 | Box Score | Recap | 7 innings |
| 4/7/2010 |
| Bethune-Cookman | 14 | at | Stetson | 3 | Box Score | Recap |
|
| 4/7/2010 |
| Coppin State | 1 | at | NC State | 18 | Box Score | Recap |
|
| 4/7/2010 |
| Delaware State |
| at | Towson |
| | Recap | CCD, campus closure |
| 4/7/2010 |
| Florida A&M | 2 | at | Alabama State | 7 | Box Score | Recap |
|
| 4/7/2010 |
| Norfolk State | 1 | at | Georgetown | 13 | Box Score | Recap |
|
| 4/7/2010 |
| UMES | 9 | at | Mount St. Mary's | 11 | Box Score | Recap |
|
| 4/10/2010 | * | Coppin State | 7 | at | Delaware State | 17 | Box Score | Recap | 8 innings, run rule |
| 4/10/2010 | * | Coppin State | 9 | at | Delaware State | 10 | Box Score | Recap | 7 innings |
| 4/10/2010 | * | North Carolina A&T | 3 | at | Bethune-Cookman | 13 | Box Score | Recap | 7 innings |
| 4/10/2010 | * | North Carolina A&T | 7 | at | Bethune-Cookman | 11 | Box Score | Recap | 7 innings |
| 4/10/2010 | * | UMES | 1 | at | Norfolk State | 11 | Box Score | Recap | 8 innings, run rule |
| 4/10/2010 | * | UMES | 1 | at | Norfolk State | 4 | Box Score | Recap | 7 innings |
| 4/11/2010 | * | Coppin State | 6 | at | Delaware State | 4 | Box Score | Recap |
|
| 4/11/2010 | * | North Carolina A&T | 3 | at | Bethune-Cookman | 13 | Box Score | Recap | 7 innings, run rule |
| 4/11/2010 | * | UMES | 4 | at | Norfolk State | 5 | Box Score | Recap |
|
| 4/12/2010 |
| Mercer | 13 | at | Florida A&M | 2 | Box Score | Recap |
|
| 4/13/2010 |
| Bethune-Cookman | 4 | at | North Florida | 5 | Box Score | Recap | 11 innings |
| 4/13/2010 |
| Delaware | 13 | at | Delaware State | 8 | Box Score | Recap |
|
| 4/13/2010 |
| Edward Waters | 12 | at | Florida A&M | 9 | Box Score | |
|
| 4/13/2010 |
| Norfolk State | 5 | at | Old Dominion | 20 | Box Score | Recap |
|
| 4/13/2010 |
| North Carolina A&T | 1 | at | Virginia Tech | 5 | Box Score | Recap |
|
| 4/14/2010 |
| Alabama State | 1 | at | Florida A&M | 9 | Box Score | Recap |
|
| 4/14/2010 |
| Bethune-Cookman | 8 | at | Florida International | 3 | Box Score | Recap |
|
| 4/14/2010 |
| Gardner-Webb | 5 | at | North Carolina A&T | 1 | Box Score | Recap |
|
| 4/14/2010 |
| George Mason | 20 | at | Coppin State | 3 | Box Score | Recap |
|
| 4/14/2010 |
| Navy | 11 | at | UMES | 3 | Box Score | Recap |
|
| 4/16/2010 |
| Coppin State | 3 | at | New Mexico | 13 | Box Score | Recap |
|
| 4/17/2010 |
| Coppin State | 6 | at | New Mexico | 8 | Box Score | Recap |
|
| 4/17/2010 | * | Florida A&M | 8 | at | Delaware State | 15 | Box Score | Recap |
|
| 4/17/2010 | * | Florida A&M | 4 | at | Delaware State | 5 | Box Score | Recap | 7 innings |
| 4/17/2010 | * | Norfolk State | 7 | at | Bethune-Cookman | 10 | Box Score | Recap |
|
| 4/17/2010 | * | Norfolk State | 2 | at | Bethune-Cookman | 9 | Box Score | Recap | 7 innings |
| 4/17/2010 | * | North Carolina A&T | 8 | at | UMES | 0 | Box Score | Recap |
|
| 4/17/2010 | * | North Carolina A&T | 10 | at | UMES | 0 | Box Score | Recap | 5 innings, run rule |
| 4/18/2010 |
| Coppin State | 3 | at | New Mexico | 29 | Box Score | Recap |
|
| 4/18/2010 | * | Florida A&M | 4 | at | Delaware State | 11 | Box Score | Recap |
|
| 4/18/2010 | * | Norfolk State | 4 | at | Bethune-Cookman | 6 | Box Score | Recap |
|
| 4/18/2010 | * | North Carolina A&T | 5 | at | UMES | 2 | Box Score | Recap |
|
| 4/20/2010 |
| Bethune-Cookman | 2 | at | Miami, Florida | 5 | Box Score | Recap |
|
| 4/20/2010 |
| Mount St. Mary's |
| at | UMES |
| | | CCD (makeup of 3/23 game) |
| 4/20/2010 |
| North Carolina A&T | 13 | at | High Point | 8 | Box Score | Recap |
|
| 4/20/2010 |
| Virginia State | 6 | at | Norfolk State | 8 | Box Score | Recap |
|
| 4/21/2010 |
| Bethune-Cookman | 2 | at | UCF | 6 | Box Score | Recap |
|
| 4/21/2010 |
| Coppin State | 4 | vs | Marshall | 10 | Box Score | Recap | 7 innings (Beckley, WV) |
| 4/21/2010 |
| Coppin State | 3 | vs | Marshall | 7 | Box Score | Recap | 7 innings (Beckley, WV) |
| 4/21/2010 |
| Delaware State | 1 | at | Georgetown | 12 | Box Score | Recap |
|
| 4/21/2010 |
| Florida A&M | 2 | at | Southern | 16 | Box Score | |
|
| 4/21/2010 |
| Norfolk State | 4 | at | Longwood | 5 | Box Score | Recap |
|
| 4/21/2010 |
| Norfolk State | 2 | at | Longwood | 8 | Box Score | Recap | 7 innings |
| 4/21/2010 |
| North Carolina A&T | 5 | at | Radford | 9 | Box Score | Recap |
|
| 4/21/2010 |
| UMES | 4 | at | Bucknell | 11 | Box Score | Recap | 7 innings, lightning |
| 4/22/2010 |
| Florida A&M | 10 | at | Southern | 11 | Box Score | |
|
| 4/24/2010 | * | Bethune-Cookman | 8 | at | Coppin State | 3 | Box Score | Recap |
|
| 4/24/2010 | * | Bethune-Cookman | 5 | at | Coppin State | 0 | Box Score | Recap | 7 innings |
| 4/24/2010 | * | Norfolk State | 7 | at | Delaware State | 8 | Box Score | Recap |
|
| 4/24/2010 | * | Norfolk State | 9 | at | Delaware State | 6 | Box Score | Recap | 7 innings |
| 4/24/2010 |
| Savannah State | 3 | at | North Carolina A&T | 18 | Box Score | Recap |
|
| 4/24/2010 |
| Savannah State | 8 | at | North Carolina A&T | 16 | Box Score | Recap | 7 innings |
| 4/24/2010 | * | UMES | 4 | at | Florida A&M | 5 | Box Score | Recap |
|
| 4/24/2010 | * | UMES | 15 | at | Florida A&M | 9 | Box Score | Recap | 7 innings |
| 4/25/2010 | * | Bethune-Cookman | 3 | at | Coppin State | 1 | Box Score | Recap |
|
| 4/25/2010 | * | Norfolk State | 13 | at | Delaware State | 12 | Box Score | Recap | 10 innings |
| 4/25/2010 |
| Savannah State | 6 | at | North Carolina A&T | 13 | Box Score | Recap |
|
| 4/25/2010 | * | UMES | 17 | at | Florida A&M | 10 | Box Score | Recap |
|
| 4/27/2010 |
| Bethune-Cookman | 9 | at | Stetson | 16 | Box Score | Recap |
|
| 4/27/2010 |
| Lehigh | 2 | at | UMES | 4 | Box Score | Recap | 7 innings (makeup of 3/3 game) |
| 4/27/2010 |
| Lehigh | 4 | at | UMES | 0 | Box Score | Recap | 7 innings (makeup of 3/3 game) |
| 4/27/2010 |
| North Carolina A&T | 1 | at | Duke | 2 | Box Score | Recap |
|
| 4/28/2010 |
| Bethune-Cookman | 4 | at | Florida Atlantic | 8 | Box Score | Recap |
|
| 4/28/2010 |
| North Carolina Central | 4 | at | Norfolk State | 11 | Box Score | Recap | 7 innings |
| 4/28/2010 |
| North Carolina Central | 5 | at | Norfolk State | 4 | Box Score | Recap | 7 innings |
| 4/28/2010 |
| Towson | 20 | at | Delaware State | 10 | Box Score | Recap |
|
| 4/29/2010 |
| Navy | 12 | at | Coppin State | 7 | Box Score | Recap |
|
| 4/30/2010 |
| Savannah State | 7 | at | Norfolk State | 5 | Box Score | Recap | 10 innings |
| 4/30/2010 | * | UMES | 1 | at | Bethune-Cookman | 11 | Box Score | Recap | 7 innings |
| 4/30/2010 | * | UMES | 1 | at | Bethune-Cookman | 12 | Box Score | Recap | 7 innings |
| 5/1/2010 | * | Coppin State | 13 | at | Florida A&M | 14 | Box Score | Recap |
|
| 5/1/2010 | * | Coppin State | 4 | at | Florida A&M | 6 | Box Score | Recap | 7 innings |
| 5/1/2010 | * | Delaware State | 2 | at | North Carolina A&T | 17 | Box Score | Recap | 7 innings |
| 5/1/2010 | * | Delaware State | 5 | at | North Carolina A&T | 11 | Box Score | Recap | 7 innings |
| 5/1/2010 |
| Savannah State | 2 | at | Norfolk State | 3 | Box Score | Recap |
|
| 5/1/2010 |
| Savannah State | 9 | at | Norfolk State | 1 | Box Score | Recap | 7 innings |
| 5/1/2010 | * | UMES | 0 | at | Bethune-Cookman | 18 | Box Score | Recap | 7 innings, run rule |
| 5/2/2010 | * | Coppin State | 18 | at | Florida A&M | 7 | Box Score | Recap |
|
| 5/2/2010 | * | Delaware State | 2 | at | North Carolina A&T | 8 | Box Score | Recap |
|
| 5/4/2010 |
| Bethune-Cookman |
| at | Florida |
| | Recap | CCD, rain |
| 5/4/2010 |
| Florida A&M |
| at | Albany State |
| | | CCD, rain |
| 5/5/2010 |
| Florida International | 10 | at | Bethune-Cookman | 4 | Box Score | Recap |
|
| 5/5/2010 |
| Jacksonville | 11 | at | Florida A&M | 8 | Box Score | Recap |
|
| 5/5/2010 |
| Navy | 4 | at | Delaware State | 3 | Box Score | Recap |
|
| 5/5/2010 | * | UMES | 3 | at | Coppin State | 4 | Box Score | Recap | makeup of 3/29 game |
| 5/5/2010 |
| VCU | 10 | at | Norfolk State | 7 | Box Score | Recap |
|
| 5/8/2010 | * | Bethune-Cookman | 19 | at | Delaware State | 13 | Box Score | Recap |
|
| 5/8/2010 | * | Bethune-Cookman | 25 | at | Delaware State | 9 | Box Score | Recap | 7 innings |
| 5/8/2010 | * | Florida A&M | 7 | at | Norfolk State | 11 | Box Score | Recap |
|
| 5/8/2010 | * | Florida A&M | 0 | at | Norfolk State | 12 | Box Score | Recap | 5 innings, run rule |
| 5/8/2010 | * | North Carolina A&T | 14 | at | Coppin State | 10 | Box Score | Recap |
|
| 5/8/2010 | * | North Carolina A&T | 23 | at | Coppin State | 2 | Box Score | Recap | 5 innings, run rule |
| 5/8/2010 |
| North Carolina Central | 2 | at | UMES | 12 | Box Score | Recap |
|
| 5/8/2010 |
| North Carolina Central | 15 | at | UMES | 19 | Box Score | Recap | 7 innings |
| 5/9/2010 | * | Bethune-Cookman | 13 | at | Delaware State | 9 | Box Score | Recap |
|
| 5/9/2010 | * | Florida A&M | 0 | at | Norfolk State | 10 | Box Score | Recap | 7 innings, run rule |
| 5/9/2010 | * | North Carolina A&T | 7 | at | Coppin State | 4 | Box Score | Recap |
|
| 5/9/2010 |
| North Carolina Central | 5 | at | UMES | 10 | Box Score | Recap |
|
| 5/9/2010 |
| North Carolina Central | 8 | at | UMES | 5 | Box Score | Recap | 7 innings |
| 5/10/2010 |
| Duke | 14 | at | North Carolina A&T | 7 | Box Score | Recap |
|
| 5/11/2010 |
| Bethune-Cookman |
| at | West Virginia |
| | Recap | CCD, inclement weather |
| 5/11/2010 |
| Campbell | 14 | at | Norfolk State | 9 | Box Score | Recap |
|
| 5/11/2010 |
| UMES | 0 | at | Old Dominion | 18 | Box Score | Recap | No-hitter for ODU's C.J. Huyett |
| 5/12/2010 |
| Bethune-Cookman | 5 | at | West Virginia | 6 | Box Score | Recap |
|
| 5/12/2010 |
| Delaware State | 0 | at | Navy | 3 | Box Score | Recap | 6 innings, rain |
| 5/12/2010 |
| Florida A&M |
| at | Alcorn State |
| | |
|
| 5/12/2010 |
| LaSalle |
| at | Coppin State |
| | | CCD, inclement weather (makeup of 3/23 game) |
| 5/14/2010 |
| Delaware State | 2 | at | New Mexico | 10 | Box Score | Recap |
|
| 5/14/2010 |
| North Carolina A&T | 8 | at | Savannah State | 6 | Box Score | |
|
| 5/15/2010 |
| Delaware State | 2 | at | New Mexico | 19 | Box Score | Recap |
|
| 5/15/2010 |
| Longwood | 8 | at | Norfolk State | 7 | Box Score | Recap |
|
| 5/15/2010 |
| Longwood | 11 | at | Norfolk State | 4 | Box Score | Recap | 7 innings |
| 5/15/2010 |
| North Carolina A&T | 11 | at | Savannah State | 3 | Box Score | |
|
| 5/15/2010 |
| North Carolina A&T | 8 | at | Savannah State | 5 | Box Score | | 7 innings |
| 5/16/2010 |
| Delaware State | 5 | at | New Mexico | 16 | Box Score | Recap |
|
| 5/16/2010 |
| Longwood | 14 | at | Norfolk State | 7 | Box Score | Recap |
|
| 5/20/2010 | MEAC-02 | Coppin State | 3 | vs | North Carolina A&T | 5 | Box Score | Recap | MEAC Tournament, Game 2 (Daytona Beach, FL) |
| 5/20/2010 | MEAC-03 | Delaware State | 4 | vs | Norfolk State | 5 | Box Score | Recap | MEAC Tournament, Game 3 (Daytona Beach, FL) |
| 5/20/2010 | MEAC-01 | UMES | 5 | vs | Bethune-Cookman | 15 | Box Score | Recap | MEAC Tournament, Game 1 (Daytona Beach, FL) (8 innings, run rule) |
| 5/21/2010 | MEAC-06 | Coppin State | 2 | vs | Delaware State | 14 | Box Score | Recap | MEAC Tournament, Game 6 (Daytona Beach, FL) (7 innings, run rule) |
| 5/21/2010 | MEAC-04 | Coppin State | 12 | vs | UMES | 8 | Box Score | Recap | MEAC Tournament, Game 4 (Daytona Beach, FL) |
| 5/21/2010 | MEAC-05 | Norfolk State | 2 | vs | North Carolina A&T | 7 | Box Score | Recap | MEAC Tournament, Game 5 (Daytona Beach, FL) |
| 5/22/2010 | MEAC-07 | Delaware State | 1 | vs | Norfolk State | 5 | Box Score | Recap | MEAC Tournament, Game 7 (Daytona Beach, FL) |
| 5/22/2010 | MEAC-09 | Norfolk State | 7 | vs | North Carolina A&T | 8 | Box Score | Recap | MEAC Tournament, Game 9 (Daytona Beach, FL) |
| 5/22/2010 | MEAC-08 | North Carolina A&T | 3 | vs | Bethune-Cookman | 7 | Box Score | Recap | MEAC Tournament, Game 8 (Daytona Beach, FL) |
| 5/23/2010 | MEAC-10 | North Carolina A&T | 4 | vs | Bethune-Cookman | 7 | Box Score | Recap | MEAC Tournament, Game 10 (Daytona Beach, FL) |
| 6/4/2010 |
| Bethune-Cookman | 3 | vs | Florida | 7 | Box Score | Recap | Gainesville Regional, Game 1 |
| 6/5/2010 |
| Florida Atlantic | 12 | vs | Bethune-Cookman | 6 | Box Score | Recap | Gainesville Regional, Game 3 |