| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/18/2009 | * | Tennessee | 7 | at | #1 LSU | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #12 Arkansas | 3 | at | #2 Georgia | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Marshall | 3 | at | #3 Rice | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #9 Miami, Florida | 4 | at | #4 North Carolina | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | Stanford | 2 | at | #5 Arizona State | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #10 Oklahoma | 3 | at | #6 Texas | 7 | FINAL | Box Score | Recap | makeup of 4/17 game |
| 4/18/2009 | * | #10 Oklahoma | 2 | at | #6 Texas | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #7 UC Irvine | 9 | at | UC Riverside | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Pacific | 14 | at | #8 Cal State Fullerton | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #11 Georgia Tech | 8 | at | Wake Forest | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #13 Baylor | 3 | at | #28 Oklahoma State | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #14 Coastal Carolina | 8 | at | High Point | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #15 Florida State | 4 | at | NC State | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #16 Mississippi | 4 | at | #22 Florida | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #17 Virginia | 6 | at | Boston College | 9 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #18 Clemson | 3 | at | Virginia Tech | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | UC Davis | 4 | at | #19 Cal Poly | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #20 East Carolina | 12 | at | Tulane | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #21 TCU |
| at | Air Force |
| Canceled | | Recap | CCD, snow |
| 4/18/2009 | * | Nebraska | 1 | at | #23 Texas A&M | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #24 San Diego State | 4 | at | New Mexico | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Southern California | 5 | at | #25 Oregon State | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #26 Ohio State | 7 | at | Purdue | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #26 Ohio State | 11 | at | Purdue | 10 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | #27 San Diego | 3 | at | St. Mary's | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Missouri | 11 | at | #29 Kansas State | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #30 Kansas | 5 | at | Texas Tech | 7 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/18/2009 | * | Albany | 10 | at | Vermont | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Albany | 3 | at | Vermont | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Stony Brook | 7 | at | Binghamton | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Stony Brook | 3 | at | Binghamton | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | UMBC | 1 | at | Maine | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | UMBC | 3 | at | Maine | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| New Jersey Tech | 9 | at | Hartford | 13 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| New Jersey Tech | 4 | at | Hartford | 3 | FINAL | Box Score | Recap | 7 innings |
| Atlantic 10 Conference |
| 4/18/2009 | * | Charlotte | 6 | at | Temple | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Duquesne | 4 | at | Richmond | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Fordham | 2 | at | Xavier | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Fordham | 6 | at | Xavier | 5 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | LaSalle | 7 | at | George Washington | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | St. Bonaventure | 0 | at | Rhode Island | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | St. Joseph's | 2 | at | Massachusetts | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | St. Louis | 9 | at | Dayton | 25 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | St. Louis | 3 | at | Dayton | 7 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| Atlantic Coast Conference |
| 4/18/2009 | * | #9 Miami, Florida | 4 | at | #4 North Carolina | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | #11 Georgia Tech | 8 | at | Wake Forest | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #15 Florida State | 4 | at | NC State | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #17 Virginia | 6 | at | Boston College | 9 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #18 Clemson | 3 | at | Virginia Tech | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Duke | 8 | at | Maryland | 4 | FINAL | Box Score | Recap | 12 innings |
| Atlantic Sun Conference |
| 4/18/2009 | * | Belmont | 6 | at | Stetson | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Campbell | 6 | at | Jacksonville | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Campbell | 5 | at | Jacksonville | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | East Tennessee State | 11 | at | South Carolina-Upstate | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | East Tennessee State | 14 | at | South Carolina-Upstate | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Kennesaw State | 9 | at | Mercer | 0 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Kennesaw State | 11 | at | Mercer | 6 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | Lipscomb | 0 | at | Florida Gulf Coast | 8 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 4/18/2009 | * | #26 Ohio State | 7 | at | Purdue | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #26 Ohio State | 11 | at | Purdue | 10 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Iowa | 10 | at | Northwestern | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Michigan State | 3 | at | Michigan | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Minnesota | 7 | at | Illinois | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Minnesota | 12 | at | Illinois | 8 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Penn State | 1 | at | Indiana | 15 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Penn State | 2 | at | Indiana | 3 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| Big 12 Conference |
| 4/18/2009 | * | #10 Oklahoma | 3 | at | #6 Texas | 7 | FINAL | Box Score | Recap | makeup of 4/17 game |
| 4/18/2009 | * | #10 Oklahoma | 2 | at | #6 Texas | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #13 Baylor | 3 | at | #28 Oklahoma State | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Nebraska | 1 | at | #23 Texas A&M | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Missouri | 11 | at | #29 Kansas State | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #30 Kansas | 5 | at | Texas Tech | 7 | FINAL | Box Score | Recap | |
| Big East Conference |
| 4/18/2009 | * | Cincinnati | 8 | at | St. John's | 16 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Georgetown | 2 | at | Connecticut | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Louisville | 7 | at | Rutgers | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Seton Hall | 2 | at | Pittsburgh | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | South Florida | 7 | at | Villanova | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | West Virginia | 6 | at | Notre Dame | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | West Virginia | 0 | at | Notre Dame | 3 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| Big South Conference |
| 4/18/2009 | * | #14 Coastal Carolina | 8 | at | High Point | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Presbyterian | 5 | at | Charleston Southern | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Presbyterian | 8 | at | Charleston Southern | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | UNC Asheville | 2 | at | Gardner-Webb | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | UNC Asheville | 5 | at | Gardner-Webb | 10 | FINAL | Box Score | Recap | moved from 4/19 |
| 4/18/2009 | * | VMI | 3 | at | Radford | 4 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | Winthrop | 3 | at | Liberty | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Winthrop | 5 | at | Liberty | 10 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| Big West Conference |
| 4/18/2009 | * | #7 UC Irvine | 9 | at | UC Riverside | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Pacific | 14 | at | #8 Cal State Fullerton | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | UC Davis | 4 | at | #19 Cal Poly | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Cal State Northridge | 3 | at | Long Beach State | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| San Jose State | 5 | at | UC Santa Barbara | 2 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/18/2009 | * | George Mason | 8 | at | VCU | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Georgia State | 5 | at | Northeastern | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Georgia State | 1 | at | Northeastern | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Hofstra | 3 | at | Old Dominion | 9 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | James Madison | 8 | at | Delaware | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Towson | 3 | at | William and Mary | 14 | FINAL | Box Score | Recap | |
| Conference USA |
| 4/18/2009 | * | Marshall | 3 | at | #3 Rice | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #20 East Carolina | 12 | at | Tulane | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Houston | 1 | at | Memphis | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | UAB | 11 | at | Southern Mississippi | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | UAB | 4 | at | Southern Mississippi | 1 | FINAL | Box Score | Recap | |
| Division I Independents |
| 4/18/2009 |
| Bryant | 10 | at | Florida Atlantic | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Bryant | 5 | at | Florida Atlantic | 13 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Dallas Baptist | 12 | at | Utah Valley State | 3 | FINAL | Box Score | Recap | makeup of 4/16 game |
| 4/18/2009 |
| Dallas Baptist | 17 | at | Utah Valley State | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Longwood | 2 | at | LeMoyne | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Longwood | 5 | at | LeMoyne | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Marist | 3 | at | New York Tech | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| New Jersey Tech | 9 | at | Hartford | 13 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| New Jersey Tech | 4 | at | Hartford | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| North Carolina Central | 5 | at | Elon | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| North Dakota | 21 | at | Concordia-Moorhead | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| North Dakota | 9 | at | Concordia-Moorhead | 10 | FINAL | Box Score | Recap | 8 innings |
| 4/18/2009 |
| Northern Colorado | 1 | at | UNLV | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Northern Colorado | 2 | at | UNLV | 15 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Savannah State | 4 | at | North Carolina A&T | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Savannah State | 2 | at | North Carolina A&T | 14 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Southern Illinois-Edwardsville | 2 | at | Southeast Missouri State | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Southern Illinois-Edwardsville | 4 | at | Southeast Missouri State | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Texas Southern | 5 | at | UT Pan American | 13 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Texas Southern | 6 | at | UT Pan American | 5 | FINAL | Box Score | Recap | 7 innings |
| Horizon League |
| 4/18/2009 | * | Butler | 4 | at | Cleveland State | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Butler | 9 | at | Cleveland State | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Wisconsin-Milwaukee | 12 | at | Youngstown State | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Wisconsin-Milwaukee | 7 | at | Youngstown State | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Wright State | 6 | at | Valparaiso | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Wright State | 1 | at | Valparaiso | 14 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Illinois-Chicago |
| at | Creighton |
| Canceled | | Recap | CCD, inclement weather |
| Ivy League |
| 4/18/2009 | * | Cornell | 8 | at | Columbia | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Cornell | 2 | at | Columbia | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Dartmouth | 1 | at | Yale | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Dartmouth | 12 | at | Yale | 9 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Harvard | 1 | at | Brown | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Harvard | 5 | at | Brown | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Princeton | 5 | at | Pennsylvania | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Princeton | 7 | at | Pennsylvania | 4 | FINAL | Box Score | Recap | |
| Metro Atlantic Athletic Conference |
| 4/18/2009 | * | Fairfield | 6 | at | Manhattan | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Fairfield | 3 | at | Manhattan | 15 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Iona | 2 | at | Niagara | 15 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Iona | 3 | at | Niagara | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Rider | 12 | at | Siena | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Rider | 10 | at | Siena | 9 | FINAL | Box Score | Recap | 8 innings |
| 4/18/2009 | * | St. Peter's | 7 | at | Canisius | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | St. Peter's | 2 | at | Canisius | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Marist | 3 | at | New York Tech | 4 | FINAL | Box Score | Recap | |
| Mid American Conference |
| 4/18/2009 | * | Akron | 4 | at | Ohio | 9 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Akron | 8 | at | Ohio | 9 | FINAL | Box Score | Recap | 13 innings (moved from 4/19, impending weather) |
| 4/18/2009 | * | Bowling Green State | 9 | at | Kent State | 12 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | Bowling Green State | 4 | at | Kent State | 9 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Buffalo | 15 | at | Miami, Ohio | 18 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Buffalo | 0 | at | Miami, Ohio | 11 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Central Michigan | 12 | at | Ball State | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Central Michigan | 4 | at | Ball State | 12 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Eastern Michigan | 6 | at | Western Michigan | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Eastern Michigan | 18 | at | Western Michigan | 6 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Toledo | 12 | at | Northern Illinois | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Toledo | 12 | at | Northern Illinois | 8 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| Mid-Eastern Athletic Conference |
| 4/18/2009 | * | Coppin State | 2 | at | Bethune-Cookman | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Coppin State | 1 | at | Bethune-Cookman | 17 | FINAL | Box Score | Recap | 5 innings, run rule |
| 4/18/2009 | * | Delaware State | 11 | at | Norfolk State | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Delaware State | 5 | at | Norfolk State | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Florida A&M | 20 | at | UMES | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Florida A&M | 11 | at | UMES | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Savannah State | 4 | at | North Carolina A&T | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Savannah State | 2 | at | North Carolina A&T | 14 | FINAL | Box Score | Recap | 7 innings |
| Missouri Valley Conference |
| 4/18/2009 | * | Evansville | 3 | at | Bradley | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Evansville | 3 | at | Bradley | 2 | FINAL | Box Score | Recap | 10 innings |
| 4/18/2009 | * | Illinois State | 11 | at | Northern Iowa | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Illinois State | 4 | at | Northern Iowa | 2 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Southern Illinois | 5 | at | Indiana State | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Southern Illinois | 3 | at | Indiana State | 5 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Wichita State | 8 | at | Missouri State | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Illinois-Chicago |
| at | Creighton |
| Canceled | | Recap | CCD, inclement weather |
| Mountain West Conference |
| 4/18/2009 | * | #21 TCU |
| at | Air Force |
| Canceled | | Recap | CCD, snow |
| 4/18/2009 | * | #24 San Diego State | 4 | at | New Mexico | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | BYU | 3 | at | Utah | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Utah | 7 | vs | BYU | 12 | FINAL | Box Score | Recap | makeup of 4/16 game (Salt Lake City, UT) |
| 4/18/2009 |
| Northern Colorado | 1 | at | UNLV | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Northern Colorado | 2 | at | UNLV | 15 | FINAL | Box Score | Recap | 7 innings |
| Northeast Conference |
| 4/18/2009 | * | Central Connecticut State | 19 | at | Quinnipiac | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Central Connecticut State | 8 | at | Quinnipiac | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Fairleigh Dickinson | 7 | at | Mount St. Mary's | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Fairleigh Dickinson | 5 | at | Mount St. Mary's | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Long Island | 4 | at | Sacred Heart | 10 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Long Island | 4 | at | Sacred Heart | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Wagner | 3 | at | Monmouth | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Wagner | 3 | at | Monmouth | 1 | FINAL | Box Score | Recap | 7 innings |
| Ohio Valley Conference |
| 4/18/2009 | * | Jacksonville State | 7 | at | Eastern Illinois | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Jacksonville State | 13 | at | Eastern Illinois | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Morehead State | 16 | at | Tennessee-Martin | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Morehead State | 5 | at | Tennessee-Martin | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Murray State | 10 | at | Eastern Kentucky | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Murray State | 8 | at | Eastern Kentucky | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Tennessee Tech | 2 | at | Austin Peay State | 6 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Tennessee Tech | 4 | at | Austin Peay State | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Southern Illinois-Edwardsville | 2 | at | Southeast Missouri State | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Southern Illinois-Edwardsville | 4 | at | Southeast Missouri State | 9 | FINAL | Box Score | Recap | 7 innings |
| Pac 10 Conference |
| 4/18/2009 | * | Stanford | 2 | at | #5 Arizona State | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Southern California | 5 | at | #25 Oregon State | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Arizona | 4 | at | Washington State | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Oregon | 5 | at | California | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Washington | 0 | at | UCLA | 13 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/18/2009 | * | Army | 6 | at | Lehigh | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Army | 12 | at | Lehigh | 0 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Bucknell | 8 | at | Navy | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Bucknell | 8 | at | Navy | 16 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Holy Cross | 1 | at | Lafayette | 10 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Holy Cross | 14 | at | Lafayette | 10 | FINAL | Box Score | Recap | |
| Southeastern Conference |
| 4/18/2009 | * | Tennessee | 7 | at | #1 LSU | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #12 Arkansas | 3 | at | #2 Georgia | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | #16 Mississippi | 4 | at | #22 Florida | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Alabama | 7 | at | Vanderbilt | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Alabama | 7 | at | Vanderbilt | 6 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | Auburn | 6 | at | South Carolina | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Kentucky | 3 | at | Mississippi State | 4 | FINAL | Box Score | Recap | 10 innings |
| Southern Conference |
| 4/18/2009 | * | Appalachian State | 7 | at | College of Charleston | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Davidson | 8 | at | Georgia Southern | 20 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Furman | 6 | at | Wofford | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Samford | 5 | at | Western Carolina | 26 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Samford | 6 | at | Western Carolina | 16 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | The Citadel | 3 | at | UNC Greensboro | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| North Carolina Central | 5 | at | Elon | 10 | FINAL | Box Score | Recap | |
| Southland Conference |
| 4/18/2009 | * | Lamar | 7 | at | UTSA | 4 | FINAL | Box Score | Recap | makeup of 4/17 game |
| 4/18/2009 | * | Lamar | 2 | at | UTSA | 7 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Sam Houston State | 12 | at | Nicholls State | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Stephen F. Austin | 6 | at | McNeese State | 1 | FINAL | Box Score | Recap | Resumption of 4/17 game |
| 4/18/2009 | * | Stephen F. Austin |
| at | McNeese State |
| Postponed | | Recap | PPD to 4/19, inclement weather |
| 4/18/2009 | * | Texas A&M-Corpus Christi | 7 | at | Southeastern Louisiana | 4 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Texas State |
| at | Northwestern State |
| Canceled | | Recap | CCD, inclement weather (makeup of 4/17 game) |
| 4/18/2009 | * | Texas State |
| at | Northwestern State |
| Postponed | | Recap | PPD to 4/19, inclement weather |
| 4/18/2009 | * | UT Arlington |
| at | Central Arkansas |
| Suspended | | Recap | Suspended to 4/19, rain (8-4 UTA, top 8) |
| Southwestern Athletic Conference |
| 4/18/2009 | * | Alabama State | 4 | at | Alcorn State | 9 | FINAL | Box Score | | 6 innings, inclement weather |
| 4/18/2009 | * | Alabama State |
| at | Alcorn State |
| Postponed | | | PPD, inclement weather |
| 4/18/2009 | * | Jackson State | 14 | at | Alabama A&M | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Jackson State | 22 | at | Alabama A&M | 2 | FINAL | Box Score | Recap | 5 innings, darkness |
| 4/18/2009 | * | Southern |
| at | Arkansas-Pine Bluff |
| Postponed | | Recap | PPD to 4/19, rain |
| 4/18/2009 | * | Southern |
| at | Arkansas-Pine Bluff |
| Postponed | | Recap | PPD to 4/20, rain |
| 4/18/2009 |
| Mississippi Valley State | 0 | at | West Florida | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Mississippi Valley State | 0 | at | West Florida | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Texas Southern | 5 | at | UT Pan American | 13 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| Texas Southern | 6 | at | UT Pan American | 5 | FINAL | Box Score | Recap | 7 innings |
| Summit League |
| 4/18/2009 | * | Centenary | 4 | at | Oral Roberts | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Centenary |
| at | Oral Roberts |
| Suspended | | Recap | Suspended to 4/19, rain (3-1 ORU, bottom 4) |
| 4/18/2009 | * | North Dakota State | 3 | at | South Dakota State | 13 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | North Dakota State | 1 | at | South Dakota State | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Oakland | 7 | at | IUPU-Fort Wayne | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Oakland | 7 | at | IUPU-Fort Wayne | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | Western Illinois | 11 | at | Southern Utah | 8 | FINAL | Box Score | Recap | |
| Sun Belt Conference |
| 4/18/2009 | * | Louisiana-Monroe | 6 | at | Middle Tennessee State | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Louisiana-Monroe | 4 | at | Middle Tennessee State | 5 | FINAL | Box Score | Recap | moved from 4/19, impending weather |
| 4/18/2009 | * | New Orleans | 5 | at | Florida International | 10 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | South Alabama |
| at | Louisiana-Lafayette |
| Suspended | | Recap | Suspended to 4/19, inclement weather (8-4 USA, bottom 7) |
| 4/18/2009 | * | Troy |
| at | Arkansas-Little Rock |
| Postponed | | Recap | PPD to 4/19, rain |
| 4/18/2009 | * | Western Kentucky | 6 | at | Arkansas State | 8 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Bryant | 10 | at | Florida Atlantic | 12 | FINAL | Box Score | Recap | |
| 4/18/2009 |
| Bryant | 5 | at | Florida Atlantic | 13 | FINAL | Box Score | Recap | |
| West Coast Conference |
| 4/18/2009 | * | #27 San Diego | 3 | at | St. Mary's | 5 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Gonzaga | 2 | at | Portland | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Loyola Marymount | 0 | at | Pepperdine | 2 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Santa Clara | 1 | at | San Francisco | 9 | FINAL | Box Score | Recap | |
| Western Athletic Conference |
| 4/18/2009 | * | Fresno State | 9 | at | Louisiana Tech | 11 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Fresno State | 5 | at | Louisiana Tech | 17 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 | * | New Mexico State | 5 | at | Nevada | 3 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Sacramento State | 2 | at | Hawaii | 1 | FINAL | Box Score | Recap | |
| 4/18/2009 | * | Sacramento State | 2 | at | Hawaii | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/18/2009 |
| San Jose State | 5 | at | UC Santa Barbara | 2 | FINAL | Box Score | Recap | |